Healthline Medical, Inc.
The Systems Approach to Aerosol Drug Delivery

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Technical specifications, as measured in our aerosol laboratory:

MM-800 Medicator Maximizer:

     Nebulizer: NEB-3A (standard)
     Material: K-resin
     Nebulizer Cup Volume: 6 mL
     Working Cup Volume: 3 - 6 mL
     Standard Air/O2 Operating Flowrate: 7 L/min
     Liquid Nebulization Rate (0.9% NaCl): 0.25 mL/min @ Flowrate of 7 L/min 
     MMAD: 1.0 µM
     Particle Size Distribution: < 0.2 µM      = 3%
0.2 - 1.0 µM = 62%
1.0 - 5.0 µM = 35%
     Nebulizer Efficiency: ~50% of drug mass is nebulized
     System Efficiency: typically, 60-65% of drug mass that is nebulized is inhaled
     Exhalation Filtration: No
     Clinical Applications: Generally central deposition for bronchial delivery of bronchodilators, mucolytics, morphine

 

MM-800A Medicator Maximizer:

     Nebulizer: NEB-3A+ (fine particle)
     Material: K-resin
     Nebulizer Cup Volume: 6 mL
     Working Cup Volume: 3 - 6 mL
     Standard Air/O2 Operating Flowrate: 7 - 10 L/min
     Liquid Nebulization Rate (0.9% NaCl): 0.14 mL/min @ Flowrate of 10 L/min
     MMAD: 0.5 µM
     Particle Size Distribution: < 0.2 µM      = 7%
0.2 - 1.0 µM = 90%
1.0 - 5.0 µM = 3%
     Nebulizer Efficiency: ~50% of drug mass is nebulized
     System Efficiency: typically, 60-65% of drug mass that is nebulized is inhaled
     Exhalation Filtration: No
     Clinical Applications: Generally peripheral deposition for endobronchial delivery of antibiotics, antirejection agents, chemotherapy agents

 

AM-602 Medicator Maximizer+Plus:

     Nebulizer: NEB-3A (standard)
     Material: K-resin
     Nebulizer Cup Volume: 6 mL
     Working Cup Volume: 3 - 6 mL
     Standard Air/O2 Operating Flowrate: 7 L/min
     Liquid Nebulization Rate (0.9% NaCl): 0.25 mL/min @ Flowrate of 7 L/min 
     MMAD: 1.0 µM
      Particle Size Distribution: < 0.2 µM      = 3%
0.2 - 1.0 µM = 62%
1.0 - 5.0 µM = 35%
     Nebulizer Efficiency: ~50% of drug mass is nebulized
     System Efficiency: typically, 60-65% of drug mass that is nebulized is inhaled
     Exhalation Filtration: Yes
     Clinical Applications: Generally central deposition for bronchial delivery of bronchodilators, mucolytics, morphine

 

AM-602A Medicator Maximizer+Plus:

     Nebulizer: NEB-3A+ (fine particle)
     Material: K-resin
     Nebulizer Cup Volume: 6 mL
     Working Cup Volume: 3 - 6 mL
     Standard Air/O2 Operating Flowrate: 7 - 10 L/min
     Liquid Nebulization Rate (0.9% NaCl): 0.14 mL/min @ Flowrate of 10 L/min
     MMAD: 0.5 µM
     Particle Size Distribution: < 0.2 µM      = 7%
0.2 - 1.0 µM = 90%
1.0 - 5.0 µM = 3%
     Nebulizer Efficiency: ~50% of drug mass is nebulized
     System Efficiency: typically, 60-65% of drug mass that is nebulized is inhaled
     Exhalation Filtration: Yes
     Clinical Applications: Generally peripheral deposition for endobronchial delivery of antibiotics, antirejection agents, chemotherapy agents

  The 1 Liter reservoir bag is made of non-latex synthetic rubber (neoprene).
  The mouthpiece is made of polypropylene.

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