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Small
Volume Nebulizers
American Association for
Respiratory Care. Clinical practice guideline. Delivery of aerosols
to the upper airway. Respir Care. 1994;39:803-7.
American Association for
Respiratory Care. Clinical practice guideline. Selection of a device
for delivery of aerosol to the lung parenchyma. Respir Care.
1996;41:647-653.
American Association for
Respiratory Care. Clinical practice guideline. Selection of aerosol
delivery device. Respir Care. 1992;37:891-897.
American Association for
Respiratory Care. Clinical practice guideline. Selection of an
aerosol delivery device for neonatal and pediatric patients. Respir
Care. 1995;40:1325-1335.
Ariyananda PL, Agnew JE,
Clarke SW, Iliffe S. Home nebuliser-compressors. Br J Hosp Med.
1995;54:489-93.
Assoufi BK, Hodson ME. High
dose salbutamol in chronic airflow obstruction: comparison of
nebulizer with Rotacaps. Respir Med. 1989;83:415-20.
Beasley CR, O'Donnell TV. Pear
shaped spacer nebuhaler compared with nebulised solution for
terbutaline administration in acute severe asthma. N Z Med J.
1985;98:854-5.
Berry RB, Shinto RA, Wong FH,
et al. Nebulizer vs spacer for bronchodilator delivery in patients
hospitalized for acute exacerbations of COPD. Chest. 1989;96:1241-6.
Birrell DJ, Clarke CW, May CS.
Terbutaline sulphate nebulizer solution: a dose-response study. Med
J Aust. 1978;2:231-2.
Blaiss MS. Aerosols and
delivery devices in asthma management [editorial]. J Asthma.
1997;34:441-2.
Campbell IA, Colman SB, Mao JH,
et al. An open, prospective comparison of beta 2 agonists given via
nebuliser, Nebuhaler, or pressurised inhaler by ambulance crew as
emergency treatment. Thorax. 1995;50:79-80.
Chan M, Lee-Pack LR, Favell K,
Chan CK. Acute pulmonary effects of three nebulizers for
administering aerosol pentamidine: comparison of Parineb to Fisoneb
and Respirgard II. J Aerosol Med. 1996;9:521-526.
Chatburn RL, McPeck M. A new system for understanding nebulizer
performance. Respir Care 2007;52(8):1037-1050.
Charoenratanakul S,
Borrirukwanit K, Lekuthai S, et al. Is driving oxygen flow rate
clinically important for nebulizer therapy in patients with COPD? J
Med Assoc Thai. 1995;78:670-6.
Cissik JH, Bode FR, Smith JA.
Double-blind crossover study of five bronchodilator medications and
two delivery methods in stable asthma. Is there a best combination
for use in the pulmonary laboratory? Chest. 1986;90:489-93.
Clay MM, Clarke SW. Wastage of
drug from nebulisers: a review. J R Soc Med. 1987;80:38-9.
Coates AL, MacNeish CF,
Meisner D, et al. The choice of jet nebulizer, nebulizing flow, and
addition of albuterol affects the output of tobramycin aerosols.
Chest. 1997;111:1206-12.
Colacone A, Afilalo M, Wolkove
N, Kreisman H. A comparison of albuterol administered by metered
dose inhaler (and holding chamber) or wet nebulizer in acute asthma.
Chest. 1993;104:835-41.
Dennis JH, Hendrick DJ. Design
characteristics for drug nebulizers. J Med Eng Technol.
1992;16:63-8.
Devadason SG, Everard ML,
Linto JM, Le Souef PN. Comparison of drug delivery from conventional
versus "Venturi" nebulizers. Eur Respir J.
1997;10:2479-83.
Diot P, Morra L, Smaldone GC.
Albuterol delivery in a model of mechanical ventilation. Comparison
of metered-dose inhaler and nebulizer efficiency. Am J Respir Crit
Care Med. 1995;152:1391-4.
Everard ML, Evans M, Milner
AD. Is tapping jet nebulisers worthwhile? Arch Dis Child.
1994;70:538-9.
Faurisson F, Dessanges JF,
Grimfeld A, et al. Nebulizer performance. Respiration. 1995;62 Suppl
1:13-8.
Gappa M, Gartner M, Poets CF,
von der Hardt H. Effects of salbutamol delivery from a metered dose
inhaler versus jet nebulizer on dynamic lung mechanics in very
preterm infants with chronic lung disease. Pediatr Pulmonol.
1997;23:442-8.
Harvey CJ, O'Doherty MJ, Page
CJ, et al. Effect of a spacer on pulmonary aerosol deposition from a
jet nebuliser during mechanical ventilation. Thorax. 1995;50:50-3.
Hess D; Aerosol therapy. In:
Dantzker DR, MacIntyre NR, Bakow ED, Eds. Comprehensive Respiratory
Care. Philadelphia: WB Saunders; 1995.
Hess D. Aerosol therapy.
Respir Care Clin North Am. 1995;1:235-263.
Hess D, Fisher D, Williams P.
Medication nebulizer performance. Effects of diluent volume,
nebulizer flow, and nebulizer brand. Chest. 1996;110:498-505.
Hess D, Horney D, Snyder T.
Medication-delivery performance of eight small-volume, hand-held
nebulizers: effects of diluent volume, gas flowrate, and nebulizer
model. Respir Care. 1989;34:717-23.
Hoffmann L, Smithline H.
Comparison of Circulaire(TM) to conventional small volume nebulizer
for the treatment of bronchospasm in the emergency department.
Respir Care. 1997;42:1170-1174.
Hughes JM, Saez J. Effects of
nebulizer mode and position in a mechanical ventilator circuit on
dose efficiency. Respir Care. 1987;32:1131-5.
Hung JC, Hambleton G, Super M.
Evaluation of two commercial jet nebulisers and three compressors
for the nebulisation of antibiotics. Arch Dis Child. 1994;71:335-8.
Hunke WA, Yu AB. Particle-size
distribution of bitolterol mesylate solution delivered by four
compressed-air nebulizer devices. Am J Hosp Pharm. 1987;44:1392-6.
Hurley PK, Smye SW, Cunliffe
H. Assessment of antibiotic aerosol generation using commercial jet
nebulizers. J Aerosol Med. 1994;7:217-28.
Idris AH, McDermott MF, Raucci
JC, et al. Emergency department treatment of severe asthma.
Metered-dose inhaler plus holding chamber is equivalent in
effectiveness to nebulizer. Chest. 1993;103:665-72.
Isaac PA, Barry JE, Vaughan
RS, et al. A jet nebuliser for delivery of topical anesthesia to the
respiratory tract. A comparison with cricothyroid puncture and
direct spraying for fibreoptic bronchoscopy. Anaesthesia.
1990;45:46-8.
Johnson CE. Principles of
nebulizer-delivered drug therapy for asthma. Am J Hosp Pharm.
1989;46:1845-55.
Kendrick AH, Smith EC, Wilson
RS. Selecting and using nebuliser equipment. Thorax. 1997;52 Suppl
2:S92-101.
Kerem E, Levison H, Schuh S,
et al. Efficacy of albuterol administered by nebulizer versus spacer
device in children with acute asthma. J Pediatr. 1993;123:313-7.
Kim CS, Garcia L, Wanner A.
Actual pentamidine dose delivered by Respigard II nebulizer. Eur
Respir J. 1995;8:2178-81.
Klassen TP, Watters LK,
Feldman ME, et al. The efficacy of nebulized budesonide in
dexamethasone-treated outpatients with croup. Pediatrics.
1996;97:463-6.
Knoch M, Wunderlich E, Geldner
S. A nebulizer system for highly reproducible aerosol delivery. J
Aerosol Med. 1994;7:229-37.
Kradjan WA, Lakshminarayan S.
Efficiency of air compressor-driven nebulizers. Chest.
1985;87:512-6.
Lin YZ, Hsieh KH. Metered dose
inhaler and nebuliser in acute asthma. Arch Dis Child.
1995;72:214-8.
Loffert DT, Ikle D, Nelson HS.
A comparison of commercial jet nebulizers. Chest. 1994;106:1788-92.
Maguire GP, Newman T,
DeLorenzo LJ, et al. Comparison of a hand-held nebulizer with a
metered dose inhaler- spacer combination in acute obstructive
pulmonary disease. Chest. 1991;100:1300-5.
Manthous CA, Hall JB, Schmidt
GA, Wood LD. Metered-dose inhaler versus nebulized albuterol in
mechanically ventilated patients. Am Rev Respir Dis.
1993;148:1567-70.
Mason JW, Miller WC.
Comparison of aerosol delivery via Circulaire nebulizer system
versus a disposable nebulizer in COPD patients. Respir Care.
1996;41:1006-1008.
Mason JW, Miller WC, Small S.
Comparison of aerosol delivery via Circulaire system vs conventional
small volume nebulizer. Respir Care. 1994;39:1157-1161.
Mestitz H, Copland JM,
McDonald CF. Comparison of outpatient nebulized vs metered dose
inhaler terbutaline in chronic airflow obstruction. Chest.
1989;96:1237-40.
Morley TF, Marozsan E,
Zappasodi SJ, et al. Comparison of beta-adrenergic agents delivered
by nebulizer vs metered dose inhaler with InspirEase in hospitalized
asthmatic patients. Chest. 1988;94:1205-10.
Nerbrink O, Dahlback M,
Hansson HC. Why do medical nebulizers differ in their output and
particle size characteristics? J Aerosol Med. 1994;7:259-76.
Newhouse MT, Fuller HD. Rose
is a rose is a rose? Aerosol therapy in ventilated patients:
nebulizers versus metered dose inhalers--a continuing controversy
[editorial; comment]. Am Rev Respir Dis. 1993;148:1444-6.
Newman SP, Pitcairn GR, Hooper
G, Knoch M. Efficient drug delivery to the lungs from a continuously
operated open-vent nebulizer and low pressure compressor system. Eur
Respir J. 1994;7:1177-81.
O'Callaghan C, Barry PW. The
science of nebulised drug delivery. Thorax. 1997;52 Suppl 2:S31-44.
O'Doherty MJ, Thomas S, Page
C, et al. Differences in relative efficiency of nebulisers for
pentamidine administration. Lancet. 1988;2:1283-6.
O'Donohue WJ Jr. Guidelines
for the use of nebulizers in the home and at domiciliary sites.
Report of a consensus conference. National Association for Medical
Direction of Respiratory Care (NAMDRC) Consensus Group. Chest.
1996;109:814-20.
O'Riordan TG, Amram JC. Effect
of nebulizer configuration on delivery of aerosolized tobramycin. J
Aerosol Med. 1997;10:13-23.
Op't Holt TB; Aerosol
generators and humidifiers. In: Barnes TA, Ed. Core Textbook of
Respiratory Care Practice. 2 ed. St. Louis: Mosby-Year Book; 1994.
Pallares DE, Pilarski BR,
Rodriguez JL, Leickly FE. A comparison of bronchodilator responses
to albuterol delivered by ultrasonic versus jet nebulization in
moderate to severe asthma. Ann Allergy Asthma Immunol.
1996;77:292-7.
Parkin PC, Saunders NR,
Diamond SA, et al. Randomised trial spacer v nebuliser for acute
asthma. Arch Dis Child. 1995;72:239-40.
Pauwels R. Inhalation device,
pulmonary deposition and clinical effects of inhaled therapy. J
Aerosol Med. 1997;10 Suppl 1:S17-21.
Pedersen S. Delivery options
for inhaled therapy in children over the age of 6 years. J Aerosol
Med. 1997;10 Suppl 1:S41-4.
Pedersen S. Inhalers and
nebulizers: which to choose and why. Respir Med. 1996;90:69-77.
Pendergast J, Hopkins J, Timms
B, Van Asperen PP. Comparative efficacy of terbutaline administered
by Nebuhaler and by nebulizer in young children with acute asthma.
Med J Aust. 1989;151:406-8.
Pisut FM. Comparison of
medication delivery by T-nebulizer with inspiratory and expiratory
reservoir. Respir Care. 1989;34:985-8.
Raimondi AC, Schottlender J,
Lombardi D, Molfino NA. Treatment of acute severe asthma with
inhaled albuterol delivered via jet nebulizer, metered dose inhaler
with spacer, or dry powder. Chest. 1997;112:24-8.
Reggio S, Bustacchini S,
Pistelli R, Valente S. Equivalence of pharmacokinetic
characteristics and bronchodilating effect between two combined
formulations of nedocromil sodium and salbutamol: MDI and nebulizer
solution. Int J Clin Pharmacol Res. 1996;16:19-27.
Rottman SJ, Robinson NE,
Birnbaum ML. Comparison of inhaled metaproterenol via metered-dose
and hand-held nebulization in prehospital treatment of bronchospasm.
Prehospital Disaster Med. 1996;11:280-4.
Saccar CL. Comparative
evaluation of therapeutic response to antiasthma drugs: dry powder
vs. conventional aerosol delivery systems. J Aerosol Med.
1996;9:89-94.
Salmeron S, Brochard L, Mal H,
et al. Nebulized versus intravenous albuterol in hypercapnic acute
asthma. A multicenter, double-blind, randomized study. Am J Respir
Crit Care Med. 1994;149:1466-70.
Salzman GA, Pyszczynski DR. A
comparison of two delivery methods for aerosolized metaproterenol
sulfate. J Asthma. 1986;23:297-301.
Shah PL, Scott SF, Geddes DM,
et al. An evaluation of two aerosol delivery systems for rhDNase.
Eur Respir J. 1997;10:1261-6.
Shim CS, Williams MH Jr.
Effect of bronchodilator therapy administered by canister versus jet
nebulizer. J Allergy Clin Immunol. 1984;73:387-90.
Smith EC, Denyer J, Kendrick
AH. Comparison of twenty three nebulizer/compressor combinations for
domiciliary use. Eur Respir J. 1995;8:1214-21.
Stapleton KW, Finlay WH,
Zuberbuhler P. An in vitro method for determining regional dosages
delivered by jet nebulizers. J Aerosol Med. 1994;7:325-44.
Summer W, Elston R, Tharpe L,
Nelson S, Haponik EF. Aerosol bronchodilator delivery methods.
Relative impact on pulmonary function and cost of respiratory care.
Arch Intern Med. 1989;149:618-23.
Thomas SH, O'Doherty MJ,
Fidler HM, et al. Pulmonary deposition of a nebulised aerosol during
mechanical ventilation. Thorax. 1993;48:154-9.
Turner MO, Gafni A, Swan D,
FitzGerald JM. A review and economic evaluation of bronchodilator
delivery methods in hospitalized patients. Arch Intern Med.
1996;156:2113-8.
Veterans Administration
Medical Center. Using Your Aerosol Machine at Home. Seattle, WA:
Seattle Veterans Administration Medical Center; 1986.
Watterberg KL, Clark AR, Kelly
HW, Murphy S. Delivery of aerosolized medication to intubated
babies. Pediatr Pulmonol. 1991;10:136-41.
Weber A, Morlin G, Cohen M, et
al. Effect of nebulizer type and antibiotic concentration on device
performance. Pediatr Pulmonol. 1997;23:249-60.
Yuksel B, Greenough A.
Comparison of the effects on lung function of two methods of
bronchodilator administration. Respir Med. 1994;88:229-33.
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