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Mechanical
Ventilation
Miller DD, Amin MM,
Palmer LB, Shah AR, Smaldone GC. Aerosol delivery and modern
mechanical ventilation: an in vitro/in vivo evaluation.
Am J Respir Crit Care Med 2003; 168:1205-1209.
Cabahug C, McPeck M, Palmer LB, Cuccia A, Atkins H, Smaldone GC. Utility of
Technetium-99m-DTPA in determining regional ventilation. J Nucl Med 37:239-244, 1996.
Chevrolet JC: "Helium Oxygen Mixtures in the Intensive Care Unit" Critical
Care(London) [online] 5(4):179-81, 2001 Aug.
Diot P, Morra L, Smaldone GC. Albuterol delivery in a model of mechanical ventilation.
Comparison of metered-dose inhaler and nebulizer efficiency. Am J Respir Crit Care Med.
1995 Oct;152(4 Pt 1):1391-4.
Duarte AG, Dhand R, Reid R, Fink JB, Fahey PJ,Tobin MJ and Jenne JW: "Serum Albuterol
Levels in Mechanically Ventilated Patients and Healthy Subjects after Metered-dose Inhaler
Administration;" Am J Respir Crit Care Med, 154(6 Pt 1):1658-63, 1996 Dec.
Dhand R, Duarte Ag, Jubran A, Jenne JW, Fink JB, Fahey PJ and Tobin MJ: "Dose-response to
Bronchodilator Delivered by Metered-dose Inhaler in Ventilator-supported Patients;" Am J
Respir Crit Care Med; 154(2 Pt 1):388-93, 1996 Aug.
Duarte AG, Fink JB and Dhand R: "Inhalation Therapy During Mechanical Ventilation,"
Respiratory Care Clinics of North America [online] [review] 7 (2):233-60, 2001 Jun.
Dhand R and Tobin MJ: "Inhaled Bronchodilator Therapy in Mechanically Ventilated Patients,"
American Journal of Respiratory and Critical Care Medicine (Pulmonary Perspective);
156:3-10, 1997.
Dubus J-C, Rhem R, Monkman AS and Dolovich M: “Delivery of Salbutamol Pressurized
Metered-dose Inhaler Administered Via Small-Volume Spacer Devices in
Intubated, Spontaneously Breathing Rabbits,” Pediatric Research 50(3):384-9, 2001 Sep.
Fernandez A, Lazaro A, Garcia A, Aragon C and Cerda E: "Bronchodilators in Patients with
Chronic Obstructive Pulmonary Disease on Mechanical Ventilation. Utilization of
Metered-dose Inhalers," Am Rev Respir Dis; 141(1):164-8,1990 Jan.
Fink JB, Dhand R, Grychowski J, Fahey PJ and Tobin MJ: "Reconciling in vitro and in vivo
Measurements of Aerosol Delivery from a Metered-dose Inhaler during Mechanical Ventilation
and Defining Efficiency-enhancing Factors," American Journal of Respiratory and Critical
Care Medicine; 159(1):63-68, 1999 Jan.
Fink JB, Tobin MJ and Dhand R: "Bronchodilator Therapy in Mechanically Ventilated
Patients," Respiratory Care; 44(1):53-69, 1999 Jan.
Fuller HD, Dolovich MB, Posmituck G, Pack WW and Newhouse MT: "Pressurized Aerosol versus
Jet Aerosol Delivery to Mechanically Ventilated Patients. Comparison of Dose to the Lungs,"
Am Rev Respir Dis; 141(2):440-4, 1990 Feb.
Gay PC, Patel HG, Nelson SB, Gilles B and Hubmayr RD: "Metered Dose Inhalers for
Bronchodilator Delivery in Intubated, Mechanically Ventilated Patients," Chest, 99(1):66-71, 1991 Jan.
Guerin C, Chevre A, Dessirier P, Poncet T, Becquemin MH, Dequin PF, Le Guellec C,
Jacques D and Fournier G: " Inhaled Fenoterol-ipratropium bromide in Mechanically
Ventilated Patients with Chronic Obstructive Pulmonary Disease;" Am J Respir Crit Care Med;
159(4 Pt 1):1036-42, 1999 Apr.
Hess D: "Aerosol Delivery During Mechanical Ventilation," Minerva Anesthesiologica [review]
68 (5):321-5, 2002 May.
Hess D: "Inhaled Bronchodilators during Mechanical Ventilation: Delivery Techniques,
Evaluation of Response, and Cost-Effectiveness," Respiratory Care; 39(2):105-22, 1994 Feb.
Lipworth BJ and Clark DJ: "Effects of Airway Calibre on Lung Delivery of Nebulised
Salbutamol," Thorax; 52(12):1036-9, 1997 Dec.
MacIntyre NR et al: "Aerosol Delivery In Intubated, Mechanically Ventilated Patients" Crit
Care Med 13(2):81-4, 1985 Feb.
Mancebo J, Amaro P, Lorino H, Lemaire F, Harf A and Brochard L: "Effects of Albuterol
Inhalation on the Work of Breathing During Weaning from Mechanical Ventilation," Am Rev
Respir Dis; 144 (1):95-100, 1991 Jul.
Manthous CA, Chatila W, Schmidt GA and Hall JB: "Treatment of Bronchospasm by Metered-dose
Inhaler Albuterol in Mechanically Ventilated Patients;" Chest; 107(1):210-3, 1995 Jan.
Manthous, C.A. and Hall, J.B. "Administration of Therapeutic Aerosols to Mechanically
Ventilated Patients," Chest, 106(2):560-71, 1994 Aug 1.
Manthous CA, Hall JB, Schmidt GA and Wood LD: "Metered-dose Inhaler versus Nebulized
Albuterol in Mechanically Ventilated Patients," Am Rev Respir Dis, 148(6 Pt 1):1567-70,
1993 Dec.
Marik P, Hogan J and Krikorian J: "A Comparison of Bronchodilator Therapy Delivered by
Nebulization and Metered-Dose Inhaler in Mechanically Ventilated Patients," Chest,
115(6):1653-7, 1999 Jun.
Martin RM, Dunn NR, Freemantle SN and Mann RD: "Risk of Non-fatal Cardiac Failure and
Ischemic Heart Disease with Long Acting â2 Agonists," Thorax; 53:558-562, 1998 Jul.
McPeck M, LeBlanc DS, Smaldone GC. Ultrasonic nebulization with a contemporary
flow-triggered ventilator. (Abstract) Respiratory Care 42:1059, 1997.
McPeck M, O'Riodan TG, Smaldone GC. Choice of mechanical ventilator: Influence on
nebulizer performance. Respiratory Care 38:887-895, August 1993.
Mouloudi E, Katsanoulas K, Anastasaki M, Askitopoulou E and Georgopoulos. Bronchodilator
Delivery by Metered-dose Inhaler in Mechanically Ventilated COPD Patients: Influence of
End-inspiratory Pause," European Respiratory Journal; 12(1):165-9, 1998 Jul.
Mouloudi E, Prinianakis G, Kondili E and Georgopoulos D: "Effect of Inspiratory Flow
Rate on beta-2 Agonist Induced Bronchodilation in Mechanically Ventilated COPD Patients,"
Intensive Care Medicine [online] [comment] 27(1):42-6, 2001 Jan.
Newman SP: "Aerosol Deposition Considerations in Inhalation Therapy," Chest, 88(2):153s-60s
1985 Aug.
O'Donahue WJ Jr, and NAMDRC Consensus Group Special Report: "Guidelines for the Use of
Nebulizers in the Home and at Domiciliary Sites," Chest; 109:814-20, 1996.
O'Riordan TG, Greco MJ, Perry RJ, Smaldone GC. Nebulizer function during mechanical
ventilation. Am Rev Respir Dis. 1992 May;145(5):1117-22.
O'Riordan TG, Palmer LB, Smaldone GC. Aerosol deposition in mechanically ventilated
patients. Optimizing nebulizer delivery. Am J Respir Crit Care Med. 1994 Jan;149(1):214-9.
Palmer LB, Smaldone GC, Simon S, O'Riordan T, Morra L. Tracheal aspirates in long-term
mechanically ventilated patients. A human model of gram-negative infection and airway
inflammation. Chest. 1995 Nov;108(5):1326-32.
Pruitt W: ""Aerosolized Antimicrobial Agents for Treating Respiratory Disease and
Infections" AARC Times, pp. 15-19, 2001 Dec.
Rubenfeld GD: “Understanding Why We Agree on the Evidence but Disagree on the Medicine,”
Respiratory Care [abs] 46(12):1442-9, 2001 December.
Sackner MA: "Auxiluary MDI Aerosol Delivery Systems," Chest, 88(2):161s-70s (Supplement),
1985 Aug.
Schleufe P, Reiffen HP and Piepenbrock S: "Effective Application of Bronchodilator Aerosols
from Metered-dose Inhalers (MDIs) via Resuscitator-bag and Adapter," Resuscitation; 39
(3):175-8, 1998 Dec.
Sivakumar D, Bosque E and Goldman SL: "Bronchodilator Delivered by Metered Dose Inhaler and
Spacer Improves Respiratory System Compliance More than Nebulizer-delivered Bronchodilator
in Ventilated Premature Infants," Pediatric Pulmonolology, 27(3):208-12, 1999 Mar.
Waugh JB and Waugh JB: "Water Accumulation in Metered Dose Inhaler Spacers Under Normal
Mechanical Ventilation Conditions," Heart & Lung 2000, 29:424-8, 2000 November/December.
Wilkins RL, Evans J and Specht L: “A Survey of Physicians to Identify Their Expectations of
Respiratory Therapists in Patient Assessment,” Respiratory Care [abs] 47(5):583-5, 2002
May.
Williams RO 3rd and Barron MK: "Influence of Temperature of the Emitted Dose of an Oral
Metered Dose Inhaler," Drug Development & Industrial Pharmacy [online] [abs] 24(11):1043-8,
1998 Nov.
Wollam PJ et al: "Prediction and Assessment of Bronchodilator Response in Mechanically
Ventilated Patients," Respiratory Care; 39(7):730-5 1994 Jul.
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