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Budesonide
Aziz I, Lipworth BJ. A bolus of inhaled budesonide rapidly
reverses airway subsensitivity and beta2-adrenoceptor
down-regulation after regular inhaled formoterol. Chest.
1999;115:623-8.
Baker JW, Mellon M, Wald J, et al. A multiple-dosing,
placebo-controlled study of budesonide inhalation suspension
given once or twice daily for treatment of persistent asthma
in young children and infants. Pediatrics.
1999;103:414-21.
Lim S, Jatakanon A, John M, et al. Effect of inhaled
budesonide on lung function and airway inflammation.
Assessment by various inflammatory markers in mild asthma. Am
J Respir Crit Care Med. 1999;159:22-30.
Merz U, Kusenbach G, Hausler M, et al. Inhaled budesonide
in ventilator-dependent preterm infants: a randomized,
double-blind pilot study. Biol Neonate. 1999;75:46-53.
Wallin A, Sandstrom T, Soderberg M, et al. The effects of
regular inhaled formoterol, budesonide, and placebo on mucosal
inflammation and clinical indices in mild asthma. Am J
Respir Crit Care Med. 1999;159:79-86.
Budesonide turbuhaler for asthma. Med Lett Drugs Ther.
1998;40:15-6.
Aaronson D, Kaiser H, Dockhorn R, et al. Effects of
budesonide by means of the Turbuhaler on the hypothalmic-
pituitary-adrenal axis in asthmatic subjects: a dose-response
study. J Allergy Clin Immunol. 1998;101:312-9.
Agertoft L, Pedersen S. Bone mineral density in children
with asthma receiving long-term treatment with inhaled
budesonide. Am J Respir Crit Care Med. 1998;157:178-83.
Barnes NC, Hallett C, Harris TA. Clinical experience with
fluticasone propionate in asthma: a meta- analysis of efficacy
and systemic activity compared with budesonide and
beclomethasone dipropionate at half the microgram dose or
less. Respir Med. 1998;92:95-104.
Barry PW, O'Callaghan C. The output of budesonide from
nebulizers. J Allergy Clin Immunol. 1998;102:321-2.
Bisgaard H, Nikander K, Munch E. Comparative study of
budesonide as a nebulized suspension vs pressurized
metered-dose inhaler in adult asthmatics. Respir Med.
1998;92:44-9.
Bourbeau J, Rouleau MY, Boucher S. Randomised controlled
trial of inhaled corticosteroids in patients with chronic
obstructive pulmonary disease. Thorax. 1998;53:477-82.
Bousquet J, Malling HJ. Immunotherapy vs inhaled budesonide
in bronchial asthma: an open, parallel comparative trial
[letter]. Clin Exp Allergy. 1998;28:778.
Busse WW, Chervinsky P, Condemi J, et al. Budesonide
delivered by Turbuhaler is effective in a dose-dependent
fashion when used in the treatment of adult patients with
chronic asthma. J Allergy Clin Immunol.
1998;101:457-63.
Cieslewicz G, Juszczyk G, Foremny J, et al. Inhaled
corticosteroid improves bronchial reactivity and decreases
symptoms in patients with mitral stenosis. Chest.
1998;114:1070-4.
Davis KC, Small RE. Budesonide inhalation powder: a review
of its pharmacologic properties and role in the treatment of
asthma. Pharmacotherapy. 1998;18:720-8.
Day J, Carrillo T. Comparison of the efficacy of budesonide
and fluticasone propionate aqueous nasal spray for once daily
treatment of perennial allergic rhinitis. J Allergy Clin
Immunol. 1998;102:902-8.
Elwood T, Morris B. Inhaled budesonide: placebo problems
[letter]. Acad Emerg Med. 1998;5:943-4.
FitzGerald JM. Effect of inhaled formoterol and budesonide
on exacerbations of asthma [letter; comment]. N Engl J Med.
1998;338:1071-2.
Fuller R, Martin P. Calculation of the minimal effective
dose for fluticasone propionate and budesonide in children
[letter; comment]. J Allergy Clin Immunol.
1998;101:289-90.
Greiff L, Andersson M, Svensson C. Effects of orally
inhaled budesonide in seasonal allergic rhinitis. Eur
Respir J. 1998;11:1268-73.
Heuck C, Wolthers OD, Kollerup G, et al. Adverse effects of
inhaled budesonide (800 micrograms) on growth and collagen
turnover in children with asthma: a double-blind comparison of
once-daily versus twice-daily administration. J Pediatr.
1998;133:608-12.
Johnson DW, Jacobson S, Edney PC, et al. A comparison of
nebulized budesonide, intramuscular dexamethasone, and placebo
for moderately severe croup. N Engl J Med.
1998;339:498-503.
Jonasson G, Carlsen KH, Blomqvist P. Clinical efficacy of
low-dose inhaled budesonide once or twice daily in children
with mild asthma not previously treated with steroids. Eur
Respir J. 1998;12:1099-104.
Klassen TP, Craig WR, Moher D, et al. Nebulized budesonide
and oral dexamethasone for treatment of croup: a randomized
controlled trial. JAMA. 1998;279:1629-32.
Nana A, Youngchaiyud P, Charoenratanakul S, et al.
High-dose inhaled budesonide may substitute for oral therapy
after an acute asthma attack. J Asthma. 1998;35:647-55.
Nelson HS, Bernstein IL, Fink J, et al. Oral
glucocorticosteroid-sparing effect of budesonide administered
by Turbuhaler: a double-blind, placebo-controlled study in
adults with moderate-to-severe chronic asthma. Pulmicort
Turbuhaler Study Group. Chest. 1998;113:1264-71.
Nelson HS, Bernstein IL, Fink J, et al. Oral
glucocorticosteroid-sparing effect of budesonide administered
by Turbuhaler: a double-blind, placebo-controlled study in
adults with moderate-to-severe chronic asthma. Chest.
1998;113:1264-71.
O'Reilly JF, Weir DC, Banham S, et al. Is high-dose
fluticasone propionate via a metered-dose inhaler and
Volumatic as efficacious as nebulized budesonide in adult
asthmatics? Respir Med. 1998;92:111-7.
O'Riordan TG, Mao Y, Otero R, et al. Budesonide affects
allergic mucociliary dysfunction. J Appl Physiol.
1998;85:1086-91.
Pauwels R. Additive effects of inhaled formoterol and
budesonide in reducing asthma exacerbations. Allergy.
1998;53:20-3.
Pauwels R. Additive effects of inhaled formoterol and
budesonide in reducing asthma exacerbations [In Process
Citation]. Allergy. 1998;53:20-3.
Pethica BD, Penrose A, MacKenzie D, et al. Comparison of
potency of inhaled beclomethasone and budesonide in New
Zealand: retrospective study of computerised general practice
records. BMJ. 1998;317:986-90.
Richter H, Seddon P. Early nebulized budesonide in the
treatment of bronchiolitis and the prevention of
postbronchiolitic wheezing. J Pediatr. 1998;132:849-53.
Rutgers SR, Koeter GH, van der Mark TW, Postma DS.
Short-term treatment with budesonide does not improve
hyperresponsiveness to adenosine 5'-monophosphate in COPD. Am
J Respir Crit Care Med. 1998;157:880-6.
Salvi S. Effect of inhaled formoterol and budesonide on
exacerbations of asthma [letter; comment]. N Engl J Med.
1998;338:1072.
Shapiro G, Bronsky EA, LaForce CF, et al. Dose-related
efficacy of budesonide administered via a dry powder inhaler
in the treatment of children with moderate to severe
persistent asthma. J Pediatr. 1998;132:976-82.
Shapiro G, Mendelson L, Kraemer MJ, et al. Efficacy and
safety of budesonide inhalation suspension (Pulmicort Respules)
in young children with inhaled steroid-dependent, persistent
asthma. J Allergy Clin Immunol. 1998;102:789-96.
Sung L, Osmond MH, Klassen TP. Randomized, controlled trial
of inhaled budesonide as an adjunct to oral prednisone in
acute asthma. Acad Emerg Med. 1998;5:209-13.
Svensson C, Andersson M, Greiff L, et al. Effects of
topical budesonide and levocabastine on nasal symptoms and
plasma exudation responses in seasonal allergic rhinitis. Allergy.
1998;53:367-74.
Swystun VA, Bhagat R, Kalra S, Jennings B, Cockcroft DW.
Comparison of 3 different doses of budesonide and placebo on
the early asthmatic response to inhaled allergen. J Allergy
Clin Immunol. 1998;102:363-7.
Tan WC, Koh TH, Hay CS, Taylor E. The effect of inhaled
budesonide on the diurnal variation in airway mechanics,
airway responsiveness and serum neutrophil chemotactic
activity in Asian patients with predominant nocturnal asthma. Respirology.
1998;3:13-20.
Thorsson L, Edsbacker S. Lung deposition of budesonide from
a pressurized metered-dose inhaler attached to a spacer. Eur
Respir J. 1998;12:1340-5.
Tos M, Svendstrup F, Arndal H, et al. Efficacy of an
aqueous and a powder formulation of nasal budesonide compared
in patients with nasal polyps. Am J Rhinol.
1998;12:183-9.
Volovitz B, Soferman R, Blau H, et al. Rapid induction of
clinical response with a short-term high-dose starting
schedule of budesonide nebulizing suspension in young children
with recurrent wheezing episodes. J Allergy Clin Immunol.
1998;101:464-9.
Wildhaber JH, Devadason SG, Wilson JM, et al. Lung
deposition of budesonide from turbuhaler in asthmatic
children. Eur J Pediatr. 1998;157:1017-22.
Wilson AM, Clark DJ, Devlin MM, et al. Adrenocortical
activity with repeated administration of one-daily inhaled
fluticasone propionate and budesonide in asthmatic adults. Eur
J Clin Pharmacol. 1998;53:317-20.
Wilson AM, McFarlane LC, Lipworth BJ. Systemic bioactivity
profiles of oral prednisolone and nebulized budesonide in
adult asthmatics. Chest. 1998;114:1022-7.
Wilson AM, Brewster HJ, Lipworth BJ. Dose-response
comparison of systemic bioactivity with inhaled budesonide and
triamcinolone acetonide in asthmatic adults. J Allergy Clin
Immunol. 1998;102:751-6.
Zetterlund A, Larsson PH, Muller-Suur C, et al. Budesonide
but not terbutaline decreases phagocytosis in alveolar
macrophages. Respir Med. 1998;92:162-6.
Agertoft L, Pedersen S. A randomized, double-blind dose
reduction study to compare the minimal effective dose of
budesonide Turbuhaler and fluticasone propionate Diskhaler. J
Allergy Clin Immunol. 1997;99:773-80.
Barlan IB, Erkan E, Bakir M, et al. Intranasal budesonide
spray as an adjunct to oral antibiotic therapy for acute
sinusitis in children. Ann Allergy Asthma Immunol.
1997;78:598-601.
Bisgaard H, Pedersen SS, Nielsen KG, et al. Controlled
trial of inhaled budesonide in patients with cystic fibrosis
and chronic bronchopulmonary Psuedomonas aeruginosa infection.
Am J Respir Crit Care Med. 1997;156:1190-6.
Booms P, Cheung D, Timmers MC, et al. Protective effect of
inhaled budesonide against unlimited airway narrowing to
methacholine in atopic patients with asthma. J Allergy Clin
Immunol. 1997;99:330-7.
Clark DJ, Lipworth BJ. Adrenal suppression with chronic
dosing of fluticasone propionate compared with budesonide in
adult asthmatic patients. Thorax. 1997;52:55-8.
Day J, Alexander M, Drouin M, et al. Budesonide aqueous
nasal spray and pressurized metered dose inhaler in the
treatment of adult patients with seasonal allergic rhinitis. Am
J Rhinol. 1997;11:77-83.
Donnelly R, Williams KM, Baker AB, et al. Effects of
budesonide and fluticasone on 24-hour plasma cortisol. A
dose-response study. Am J Respir Crit Care Med.
1997;156:1746-51.
du Toit JI, Anderson SD, Jenkins CR, et al. Airway
responsiveness in asthma: bronchial challenge with histamine
and 4.5% sodium chloride before and after budesonide. Allergy
Asthma Proc. 1997;18:7-14.
Evans DJ, Taylor DA, Zetterstrom O, et al. A comparison of
low-dose inhaled budesonide plus theophylline and high-dose
inhaled budesonide for moderate asthma. N Engl J Med.
1997;337:1412-8.
Godden CW, Campbell MJ, Hussey M, Cogswell JJ. Double blind
placebo controlled trial of nebulised budesonide for croup. Arch
Dis Child. 1997;76:155-8.
Grahnen A, Jansson B, Brundin RM, et al. A dose-response
study comparing suppression of plasma cortisol induced by
fluticasone propionate from Diskhaler and budesonide from
Turbuhaler. Eur J Clin Pharmacol. 1997;52:261-7.
Greiff L, Andersson M, Svensson C, et al. Effects of two
weeks of topical budesonide treatment on microvascular
exudative responsiveness in healthy human nasal airways. Eur
Respir J. 1997;10:841-5.
Heuck C, Wolthers OD, Hansen M, Kollerup G. Short-term
growth and collagen turnover in asthmatic adolescents treated
with the inhaled glucocorticoid budesonide. Steroids.
1997;62:659-64.
Lildholdt T, Rundcrantz H, Bende M, Larsen K.
Glucocorticoid treatment for nasal polyps. The use of topical
budesonide powder, intramuscular betamethasone, and surgical
treatment. Arch Otolaryngol Head Neck Surg.
1997;123:595-600.
Lipworth BJ, Clark DJ, McFarlane LC. Adrenocortical
activity with repeated twice daily dosing of fluticasone
propionate and budesonide given via a large volume spacer to
asthmatic school children. Thorax. 1997;52:686-9.
Nikolaizik WH, Preece MA, Warner JO. One year follow-up
study of endocrine and lung function of asthmatic children on
inhaled budesonide. Eur Respir J. 1997;10:2596-601.
Nursoy MA, Bakir M, Barlan IB, Basaran MM. The course of
chickenpox in asthmatic children receiving inhaled budesonide.
Pediatr Infect Dis J. 1997;16:74-7.
Osterman K, Carlholm M, Ekelund J, et al. Effect of 1 year
daily treatment with 400 microg budesonide (Pulmicort
Turbuhaler) in newly diagnosed asthmatics. Eur Respir J.
1997;10:2210-5.
Pauwels RA, Lofdahl CG, Postma DS, et al. Effect of inhaled
formoterol and budesonide on exacerbations of asthma. N
Engl J Med. 1997;337:1405-11.
Pelkonen AS, Nikander K, Turpeinen M. Jet nebulization of
budesonide suspension into a neonatal ventilator circuit:
synchronized versus continuous nebulizer flow. Pediatr
Pulmonol. 1997;24:282-6.
Sekerel BE, Tuncer A, Saraclar Y, Adalioglu G. Inhaled
budesonide reduces lung hyperinflation in children with
asthma. Acta Paediatr. 1997;86:932-6.
Shaikh WA. Immunotherapy vs inhaled budesonide in bronchial
asthma: an open, parallel, comparative trial. Clin Exp
Allergy. 1997;27:1279-84.
Stern MA, Dahl R, Nielsen LP, et al. A comparison of
aqueous suspensions of budesonide nasal spray (128 micrograms
and 256 micrograms once daily) and fluticasone propionate
nasal spray (200 micrograms once daily) in the treatment of
adult patients with seasonal allergic rhinitis. Am J Rhinol.
1997;11:323-30.
Struijs A, Mulder H. The effects of inhaled glucocorticoids
on bone mass and biochemical markers of bone homeostasis: a
1-year study of beclomethasone versus budesonide. Neth J
Med. 1997;50:233-7.
Toogood JH, White FA, Baskerville JC, et al. Comparison of
the antiasthmatic, oropharyngeal, and systemic glucocorticoid
effects of budesonide administered through a pressurized
aerosol plus spacer or the Turbuhaler dry powder inhaler. J
Allergy Clin Immunol. 1997;99:186-93.
Vikre-Jorgensen J, Agertoft L, Pedersen S. Dose titration
of nebulized budesonide in young children. Pediatr Pulmonol.
1997;23:270-7.
Wang D, Smitz J, De Waele M, Clement P. Effect of topical
applications of budesonide and azelastine on nasal symptoms,
eosinophil count and mediator release in atopic patients after
nasal allergen challenge during the pollen season. Int Arch
Allergy Immunol. 1997;114:185-92.
Inhaled budesonide and adrenaline for croup. Drug Ther
Bull. 1996;34:23-4.
Arnon S, Grigg J, Silverman M. Effectiveness of budesonide
aerosol in ventilator-dependent preterm babies: a preliminary
report. Pediatr Pulmonol. 1996;21:231-5.
Ayres JG, Campbell LM. A controlled assessment of an asthma
self-management plan involving a budesonide dose regimen.
OPTIONS Research Group. Eur Respir J. 1996;9:886-92.
Boorsma M, Andersson N, Larsson P, Ullman A. Assessment of
the relative systemic potency of inhaled fluticasone and
budesonide. Eur Respir J. 1996;9:1427-32.
Clark DJ, Grove A, Cargill RI, Lipworth BJ. Comparative
adrenal suppression with inhaled budesonide and fluticasone
propionate in adult asthmatic patients. Thorax.
1996;51:262-6.
Clark DJ, Clark RA, Lipworth BJ. Adrenal suppression with
inhaled budesonide and fluticasone propionate given by large
volume spacer to asthmatic children. Thorax.
1996;51:941-3.
de Blic J, Delacourt C, Le Bourgeois M, et al. Efficacy of
nebulized budesonide in treatment of severe infantile asthma:
a double-blind study. J Allergy Clin Immunol.
1996;98:14-20.
de Jong JW, van der Mark TW, Koeter GH, Postma DS. Rebound
airway obstruction and responsiveness after cessation of
terbutaline: effects of budesonide. Am J Respir Crit Care
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Fitzgerald D, Mellis C, Johnson M, et al. Nebulized
budesonide is as effective as nebulized adrenaline in
moderately severe croup. Pediatrics. 1996;97:722-5.
Fornhem C, Dahlback M, Kumlin M, et al. Effects of local
and systemic budesonide on allergen-induced airway reactions
in the pig. Br J Pharmacol. 1996;118:989-97.
Gauvreau GM, Doctor J, Watson RM, et al. Effects of inhaled
budesonide on allergen-induced airway responses and airway
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Hoekx JC, Hedlin G, Pedersen W, et al. Fluticasone
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asthmatic children using powder devices at a dosage of 400
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Klassen TP, Watters LK, Feldman ME, et al. The efficacy of
nebulized budesonide in dexamethasone-treated outpatients with
croup. Pediatrics. 1996;97:463-6.
Lonnebo A, Grahnen A, Jansson B, et al. An assessment of
the systemic effects of single and repeated doses of inhaled
fluticasone propionate and inhaled budesonide in healthy
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Morice AH, Morris D, Lawson-Matthew P. A comparison of
nebulized budesonide with oral prednisolone in the treatment
of exacerbations of obstructive pulmonary disease. Clin
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Pedersen B, Dahl R, Karlstrom R, et al. Eosinophil and
neutrophil activity in asthma in a one-year trial with inhaled
budesonide. The impact of smoking. Am J Respir Crit Care
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Piquet J, Zuck P, Dennewald G, et al. Equally efficacious
asthma management with budesonide 800 micrograms administered
by Turbuhaler or with beclomethasone dipropionate > or =
1500 micrograms given through a pressurized metered-dose
inhaler with spacer. The French Budesonide Trial Group. Adv
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Reid A, Murphy C, Steen HJ, et al. Linear growth of very
young asthmatic children treated with high-dose nebulized
budesonide. Acta Paediatr. 1996;85:421-4.
Synnerstad B, Lindqvist N. A clinical comparison of
intranasal budesonide with beclomethasone dipropionate for
perennial non-allergic rhinitis: a 12 month study. Br J
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Wilding PJ, Clark MM, Oborne J, et al. Effect of regular
terbutaline on the airway response to inhaled budesonide. Thorax.
1996;51:989-92.
Alberts C, van der Mark TW, Jansen HM. Inhaled budesonide
in pulmonary sarcoidosis: a double-blind, placebo- controlled
study. Dutch Study Group on Pulmonary Sarcoidosis. Eur
Respir J. 1995;8:682-8.
Fuller RW, Sharma RK, Cripps A. Lung deposition of
budesonide from Turbuhaler is twice that from a pressurized
metered-dose inhaler (P-MDI) [letter]. Eur Respir J.
1995;8:2194-5.
Tjwa MK. Budesonide inhaled via Turbuhaler: a more
effective treatment for asthma than beclomethasone
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Volovitz B, Kauschansky A, Nussinovitch M, Harel L, Varsano
I. Normal diurnal variation in serum cortisol concentration in
asthmatic children treated with inhaled budesonide. J
Allergy Clin Immunol. 1995;96:874-8.
Weiner P, Weiner M, Azgad Y. Long term clinical comparison
of single versus twice daily administration of inhaled
budesonide in moderate asthma. Thorax. 1995;50:1270-3.
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therapy for patients with stable COPD. Chest.
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Youngchaiyud P, Permpikul C, Suthamsmai T, Wong E. A
double-blind comparison of inhaled budesonide, long-acting
theophylline, and their combination in treatment of nocturnal
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Matthys H, Muller S, Herceg R. Theophylline vs. budesonide
in the treatment of mild-to-moderate bronchial asthma. Respiration.
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of budesonide Turbuhaler compared with that of beclomethasone
dipropionate pMDI with volumatic spacer. A 2-year randomized
study in 102 asthma patients. Allergy. 1994;49:833-6.
Agertoft L, Pedersen S. Importance of the inhalation device
on the effect of budesonide. Arch Dis Child.
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Davies B. A comparison of beclomethasone dipropionate and
budesonide in the treatment of asthma. Br J Clin Pract.
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Pedersen S, Steffensen G, Ohlsson SV. The influence of
orally deposited budesonide on the systemic availability of
budesonide after inhalation from a Turbuhaler. Br J Clin
Pharmacol. 1993;36:211-4.
Vendelo Johansen L, Illum P, Kristensen S, et al. The
effect of budesonide (Rhinocort) in the treatment of small and
medium-sized nasal polyps. Clin Otolaryngol.
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Arnon S, Grigg J, Nikander K, Silverman M. Delivery of
micronized budesonide suspension by metered dose inhaler and
jet nebulizer into a neonatal ventilator circuit. Pediatr
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Laitinen LA, Laitinen A, Haahtela T. A comparative study of
the effects of an inhaled corticosteroid, budesonide, and a
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Lodrup Carlsen KC, Nikander K, Carlsen KH. How much
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budesonide for chronic wheezing under 18 months of age. Arch
Dis Child. 1992;67:285-8.
Haahtela T, Jarvinen M, Kava T, et al. Comparison of a beta
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Wolthers OD, Pedersen S. Growth of asthmatic children
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Dahl R, Pedersen B, Hagglof B. Nocturnal asthma: effect of
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Engel T, Heinig JH, Malling HJ, et al. Clinical comparison
of inhaled budesonide delivered either via pressurized metered
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Selroos OB. Use of budesonide in the treatment of pulmonary
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Compiled 7/30/99. Based on MedLine
Update through June, 1999. A
Scanlan Bibliography
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