Healthline Medical, Inc.
The Systems Approach to Aerosol Drug Delivery

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 Frequently Asked Questions  (FAQs)


FAQ #3 -- Doesn't the reservoir bag get contaminated?

Answer -- Actually, no.  The reservoir bag does not get contaminated because it is isolated from the patient's exhalation by the flapper.  And, unlike most other small volume nebulizers, the nebulizer is also isolated from the patient's exhalation.

However, even if the reservoir bag did become contaminated, it would not transfer the contamination to either the nebulizer or the patient.

How do we know this?  We studied it in our on-site aerosol lab using a readily detectable radioactive tracer to simulate bacterial contamination of the reservoir bag.

In a nutshell, when we deliberately contaminated the inside of a clean reservoir bag with 3 ml of radiolabeled albuterol (99mTc), we were unable, in 6 experiments, to recover any radioactivity in either the nebulizer or a HEPA filter at the patient airway opening after up to 20 minutes of breathing.  You can read the entire study in the "White Papers" section of our web site.

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